Although the theoretical risk of prolonged colonization and chronic GLP-1 secretion is well-founded, there is currently no practical evidence from long-term clinical or preclinical studies demonstrating stable persistence, sustained GLP-1 production, or associated clinical effects
What should I do if its high or low
In a randomized, placebo-controlled study of 495 patients with intermittent claudication, 2 g/day of propionyl-L-carnitine for 12 months significantly increased maximal walking distance and the distance walked prior to the onset of claudication in patients whose initial maximal walking distance was less than 250 meters (m), but no effect was seen in patients who had an initial maximal walking distance greater than 250 m (65)
However, methotrexate therapy requires careful monitoring due to its potential for adverse effects, particularly hepatotoxicity (Malaviya 2016
The participants, who were stable at the start of the study, continued to be stable as the study went on, meaning being in ketosis didnt tip them toward depression or mania
Do not administer it to children without consulting their doctor first