There is no universal "add 1 mL" rule
I had my first PRP treatment last week
It represents their guarantee that, up to that date, the product remains sterile and the benzyl alcohol concentration is effective, provided it has been stored correctly (at controlled room temperature)
Errors during reconstitution or storage directly impact effectiveness and safety
For example, in a new study, patients who first used a daily topical treatment gel containing 0.1% adapalene and 2.5% benzoyl peroxide for 2-4 weeks before undergoing 3 treatments with Sebacia, spaced 1-2 weeks apart, saw an improvement of 66% at 3 months, as compared to those who had Sebacia alone (in the clinical trials), and showed 49% improvement at 3 months
2,97 Lactation B12 requirements are increased during breastfeeding