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Esophageal cancer (EC) In recent decades, the epidemiology of esophageal cancer (EC) has shown striking global trends and differences

Histopathological evaluation was performed by a blinded pathologist using light microscopy

First, before PSM, baseline characteristics differed significantly between groups, which could have affected the outcome analysis

Its 39-residue sequence is engineered around a GIP backbone rather than the more commonly modified GLP-1 scaffold, a design choice that fundamentally shapes its receptor pharmacology and distinguishes it from earlier dual-agonist candidates that simply chained GLP-1 and glucagon sequences together

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