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In vivo and in vitro studies have reported that EE itself is biotransformed for excretion mainly by glucuronidation (85%) and sulfation (12%) and that hydroxylation (mainly by CYP3A4 and CYP2A9 on C2) occurs only at low levels 22

Reconstitute with bacteriostatic water or sterile water

Reference: Staresinic M, Sebecic B, Patrlj L, et al

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Both DPP-4 inhibitors and GLP-1 RAs have demonstrated safety in robust cardiovascular outcome trials, while several GLP-1 RAs have been shown to significantly reduce the risk of major adverse cardiovascular events in persons with T2DM with pre-existing cardiovascular disease (CVD)

It helps in the activation of enzymes and plays an important role in the removal of toxins from the body