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For the in vitro experiments, a murine macrophage cell line RAW 264.7 was used

PlushCare integrates nurse practitioners and offers more detailed metabolic screening in some cases

High-quality human clinical trials are lacking

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Cleveland Clinic: Creatine Nutrients: Risk of Adverse Outcomes in Females Taking Oral Creatine Monohydrate: A Systematic Review and Meta-Analysis Nutrients: Creatine Supplementation Beyond Athletics: Benefits of Different Types of Creatine for Women, Vegans, and Clinical PopulationsA Narrative Review The Gut Health MD Mayo Clinic: Diarrhea: When to See a Doctor Mayo Clinic: Diarrhea Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance Cleveland Clinic: Is the Creatine Loading Phase Worth Doing? Lynn Grieger, RDN, CDCES Medical Reviewer Lynn Grieger is a registered dietitian-nutritionist, certified diabetes care and education specialist, certified personal trainer, and certified health and wellness coach