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Targeting lipid GPCRs to treat type 2 diabetes mellitus - progress and challenges

Literature search strategy A comprehensive literature review was conducted to identify relevant studies

It is important to note that tesofensine is an investigational drug and has not been approved for commercial use

Laxatives, especially when used frequently, can also lead to significant fluid loss

The pathway reconstitution experiments allowed us to assess the TMA forming capacity of gut microbes which is related to human cardiovascular health