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El GLP-1 puede activar las neuronas del complejo dorsal del vago, lo que puede iniciar un reflejo vagal eferente mediado por el sistema nervioso parasimptico que culmine en la secrecin de acetilcolina en los islotes pancreticos activando los receptores muscarnicos y estimulando la movilizacin de Ca 2+ en la CBP, lo cual describira un efecto neuronal insulinotrpico rpido de esta hormona 21

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Additionally, the inflammasome induces peripheral blood monocytes to transform into foam cells and undergo apoptosis, resulting in plaque depositions within arteries (Tan et al., 2023)

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