Chronic depression, obesity, terrible sleep, raising 3 kids, startup founder/CEO grind culture behavior (and even growing up w/ excess sugar, sun exposure, junk food). Its worth remembering: Zero (@bryan_johnson) July 18, 2023 1) My body and mind were trashed in every way for 23 years
Cysteine, glutathione, and thiol redox balance in astrocytes
The newest and most powerful research on mental health centers around how early trauma, infection, and stress cause life-long changes (more here)
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Copper is a vital cofactor for methionine synthase, and its deficiency can impair the enzymes function, disrupting methylation reactions
Applications of single-cell epigenomics Studies have revealed alterations of DNA methylation and histone modifications in OA chondrocytes that may affect gene expression and thus participate in the pathogenesis of OA [120]