It is naturally produced in human gastric juice, but is also found in small amounts in the gastric juice of other mammals
Various scientific demarcations are used for this purpose
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Hum Exp Toxicol 40(9):15371544
It may integrate signaling between osteoblasts and osteoclasts via the receptor activator of nuclear factor kappa- (RANK)/receptor activator of nuclear factor kappa- ligand (RANKL)/osteoprotegerin (OPG) pathway, thereby influencing the balance of bone remodeling [131, 141]
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