James Grant of Michigan BCBS summarized the frustration: "We were wasting millions of dollars, and people did not even see true benefit." From an actuarial perspective, the math was devastating
Biochemical outcomes Glucose There was a significant reduction in fasting plasma glucose (FPG) in the inulin group compared to control at week nine (0.23 0.17 mmol/L, n = 20 vs 0.44 0.24 mmol/L, n = 19, p = 0.005) after controlling for weight loss but the change at week 18 was no longer significant (0.40 0.19 mmol/L, n = 20 vs 0.16 0.23 mmol/L, n = 18, p = 0.08) (Fig
Furthermore, these treatments are not yet reimbursed by social security health system in France
Health plans should work alongside PBMs and GLP-1 manufacturers to drive down costs, unlock rebates to further mitigate cost challenges and enhance drug commercialization (e.g., joint production partnerships, marketing partnerships)
It includes positron emission tomography-magnetic resonance (PET MRI) studies of plaque inflammation (plaque 18 F-FDG and 68 Ga-DOTATATE uptake), MRI for plaque morphology and burden, as well as biomarkers, proteomics and RNA profiling, myocardial perfusion reserve and changes in carotid artery total wall volume
Key Differences: Prescription vs
