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DBS targeting the ventral medial prefrontal cortex is thought to exert its antidepressant-like and cognitive enhancement effect by increasing expression of BDNF, Akt, and mammalian target of rapamycin (mTOR), and observed to restore stress-induced synaptic loss in the hippocampus (131)

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[Ru (DPP) 3 ] Cl 2 probe for O 2 Raw 264.7 cells were seeded into a 12-well plate and subjected to hypoxic conditions with LPS induction for 24 h to promote differentiation into inflammatory cells