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[DOI] [PubMed] [Google Scholar] 105.Li Z., Shimada Y., Uchida S., Maeda M., Kawabe A., Mori A., Itami A., Kano M., Watanabe G., Imamura M

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These changes are associated with increased systemic inflammation markers, and some investigations have made correlations of microbial imbalance with faster disease progression (Obrenovich et al., 2020)

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Serotonin Serotonin is synthesized through a two-step process involving a tetrahydrobiopterin-dependent hydroxylation reaction (catalyzed by tryptophan-5-monooxygenase, also called tryptophan hydroxylase) and then a decarboxylation catalyzed by DOPA decarboxylase (also known as aromatic L-amino acid decarboxylase)