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doi: 10.1158/0008-5472.CAN-21-1109 140 FauciJMSabbatinoFWangYLondoo-JoshiAIStraughnJMJr.LandenCNet al

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In addition to the Leu198Leu genotype in the GPx1 gene, the Ala16Ala genotype in the manganese superoxide dismutase ( MnSOD ) gene, the most significant enzyme that protects against ROS in the human body [90], was also associated with an increased risk of breast cancer [91]