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Additionally, baicalein, an active component from the traditional Chinese medicine Scutellaria baicalensis, functions as a potent iron chelator and inhibits erastin-induced Fe 2+ production under normal cellular conditions, potentially playing a key role in regulating organismal iron homeostasis and inhibiting Fenton reactions (71)

Alhadeff AL, Grill HJ

Cons: High cost

The absence of a documented interaction does not equate to safety or lack of clinical concern

10.1210/er.2002-0005 28 De MillianoI.Van HattumD.KetJ

Some of the dual and triple agonists have already shown initial successes in clinical trials, although the molecular mechanisms underlying their multiplexed pharmacology remain elusive