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Anatomical disposition of the muscle layers on the rectum, especially in the anterior and posterior walls, promoting a major resistance to intraluminal variations could justify the lower prevalence of this condition compared to colonic diverticulosis

Hepatol Int 11:221241

Chronic cholecystitis The physical presence of stones in the gallbladder can cause chronic mechanical irritation of the gallbladder wall

Mitochondrial abnormalities have also been associated with point mutations in Hsp70 chaperone that makes it aggregation prone, thereby, increasing iron and free-radical load 15,16,17

Wires Comput

For example, most clinical trials reporting weight loss outcomes involved participants taking 2.4 mg of semaglutide, which is the maximum dose for Wegovy