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Key points: GLP-1 receptor agonists (GLP-1s) are a class of medications that mimic the actions of the hormone GLP-1, which helps regulate hunger and blood sugar levels GLP-1s help the pancreas release more insulin, delay stomach emptying, and reduce appetite Wegovy and Trulicity mimic the action of GLP-1 and decrease appetite and blood sugar levels 2 Wegovy vs Trulicity: Which is better for weight loss