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La L-carnitina es un compuesto similar a un aminocido que se produce naturalmente en el cuerpo a partir de aminocidos esenciales, lisina y metionina
Exenatide (twice-daily) and lixisenatide are GLP-1 receptor agonists based on exendin-4 that overcome cleavage by DPP-4, however, their half remains short with ~ 24 h due to renal elimination
doi: 10.1016/0006-8993(86)90769-9 76
Diabetes-induced microvascular alterations, including the thickening of the capillary basement membrane and endothelial hyperplasia, diminish blood flow to nerves, leading to ischemia and subsequent nerve fiber damage
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