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However, there is evidence which more strongly supports that common MTHFR variants are not a prothrombotic genetic factor

It doesn't replace the original

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In Metal-Based Composite Nanomaterials (eds Jun Yang & Hui Liu) 1129 (Springer International Publishing, 2015)

The lack of the effect of iron and amlodipine on cardiac electrical activity was corroborated by electrocardiographic measurements