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Its version without Drug Affinity Complex (DAC) typically has a shorter half-life measured in hours, while the DAC-modified version can remain active for several days because the modification slows degradation since the DAC component allows the peptide to bind to albumin in the bloodstream, extending circulation time

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Clinical comparison of tofogliflozin and empagliflozin based on an analysis of 24-h accumulated urine in Japanese patients with type 2 diabetes mellitus

FDA pregnancy category classification guides prescribing but does not eliminate uncertainty

FujitaHMoriiTFujishimaHSatoTShimizuTHosobaMet alThe protective roles of GLP-1R signaling in diabetic nephropathy: possible mechanism and therapeutic potential

A guide for prescribing medicines to manage overweight and obesity (TA1026 resource)