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note that tirzepatide is also available as Mounjaro, which holds a separate MHRA authorisation for the treatment of type 2 diabetes these are distinct licensed indications and should not be confused [14] [15] These medicines are supported by robust clinical trial data, have established safety profiles, and are prescribed within regulated frameworks with appropriate monitoring

PCOS is a heterogeneous condition in terms of pathogenesis and clinical manifestations, whose mechanisms are not fully understood

A randomized, double-blind, placebo-controlled study conducted in 40 patients with type 2 diabetes with microalbuminuria found that high-dose thiamin supplementation (300 mg/day) decreased excretion of urinary albumin over a three-month period (87)