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62 A case series linked the use of semaglutide or tirzepatide with an increased risk of NAION, sometimes after a single dose, including in one patient without diabetes and in another who experienced symptoms in both eyes following separate doses

Following secretion, PYY is rapidly cleaved by dipeptidyl peptidase-4 (DPP-4) to its active form (PYY 3-36) acting on neuropeptide Y receptor type 2 (Y2R)

Hydration and Preparation on Injection Day Staying well-hydrated before and after your semaglutide injection supports medication absorption and reduces nausea risk

Hyperpigmentation is a condition in which certain areas of the skin become darker and stand out from the rest

While this means that they both mimic naturally occurring hormones in the body, tirzepatide goes an extra step and operates on the glucose-dependent insulinotropic polypeptide (GIP) hormone as well