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There's broad clinical consensus on this point, and it's reflected in the FDA's updated labeling position as well

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In addition, plasma creatinine was higher in dogs fed CCC compared to CON ( P = 0.0458) and tended to be higher compared to dogs fed MET ( P = 0.0861) at 240 min post-meal

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With the electrodes already in place in patients' brains, the Penn team thought there might be a rare chance to observe the effect of another GLP-1, tirzepatide, on the NAc