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Mechanistically, a microglial inflammation-oxidative stress feedforward loop perpetuates injury: Activated microglia secrete neurotoxins, impairing neuronal mitochondrial function and antioxidant capacity (such as GPX4), thus increasing ROS leakage

Effects of diet based on IgG elimination combined with probiotics on migraine plus irritable bowel syndrome

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This increase at low oxidative stress is due to the stimulation of CBS and GCS that increases GSH synthesis and concentration, and therefore the rate of export

Introduction The term oxidative stress (OS) applies when increased amounts of reactive oxygen species (ROS) surpass the antioxidant (AOX) capacity that naturally offers the protective balance ( Hence, AOX therapy to enhance fertility by protecting against the harmful effects of ROS is theoretically feasible

insulin resistance/obesity (110, 116)