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Ratjen et al., 2015

GLP-1 Receptor Agonists: Harnessing the Power of GLP-1 Given the short lifespan of natural GLP-1, scientists developed a class of drugs called GLP-1 receptor agonists (GLP-1 RAs)

most reactions are mild and improve by reducing the dose or changing formulas

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The study that shed light on the protein machinery involved in the extrinsic cell death pathway in RBCs is that of Mandal et al

CHALLENGES TO DEVELOPMENT In developing the second-generation amylin-analog cagrilintide there were 2 main barriers: (1) to prevent amylin protein aggregation and (2) to extend the amylin-analogs half-life