Gradual reduction allows your appetite-regulating hormones to adjust without triggering intense rebound hunger
Svetlana Mojsov, Joel Habener, and Dan Drucker at Massachusetts General Hospital and Jens Juul Holst at the University of Copenhagen, who presented an early understanding of the structure and function of GLP-1
GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) mimic this hormone to slow gastric emptying, reducing appetite and curbing food cravings
This phenomenon can be attributed to the presence of bile salt hydrolase enzymes, which are predominantly found within the phyla Firmicutes and Bacteroidetes, particularly in the Clostridium clusters [167]
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In patients 65 years treated with insulin, additional frequent glucose monitoring via fingersticks or continuous glucose monitoring (CGM) is recommended [215]