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Normally: Angiotensin I (ACE) Angiotensin II Angiotensin II causes: Vasoconstriction Aldosterone release Increased blood pressure After Captopril: Angiotensin II Vasoconstriction Aldosterone Blood pressure Bradykinin (causes cough) Indications Hypertension Heart failure Post-myocardial infarction Diabetic nephropathy Left ventricular dysfunction Dosage Hypertension: Start: 12.525 mg 23 times daily Maintenance: 2550 mg 23 times daily Heart Failure: Start low (6.25 mg TDS) Titrate gradually Dose adjustment needed in renal impairment

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Oral pigmented lesions: Clinicopathologic features and review of the literature.Medicina Oral, Patologia Oral y Cirugia Bucal

These interviews were conducted across major regions, namely, North America, Europe, the Asia Pacific, and the Rest of the World (including Latin America, the Middle East, and Africa)

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