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Local ethics committee approval was obtained from Van Yznc Yl University Medical Faculty Hospital before blood samples were taken (decision number:03 and date:10.02.2021)

Useful anti-aggregation additives include, by way of example only, urea, guanidinium chloride, simple amino acids such as glycine or arginine, sugars, polyalcohols, polysorbates, polymers such as polyethylene glycol and dextrans, alkyl saccharides, such as alkyl glycoside, and surfactants

A liposome consists of either a single-layered or multi-layered phospholipid structure with an aqueous core

New insights into the fatty acid-binding protein (FABP) family in the small intestine

The pharmacokinetics of LY3437943 (retatrutide) support once-weekly administration due to an elimination half-life of approximately 6 days. Jastreboff AM et al., Nature Medicine, 2023 This extended half-life is made possible by attaching a fatty acid chain to the peptide, allowing it to bind to albumin a common protein in your blood that acts like a slow-release carrier

93,94,95,96 Dysfunctional lysosomes and genetic variants such as IRGM further exacerbate disease progression