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Similarly, patients with type 2 diabetes were also represented in many studies 51,53,54,56,57,59,62,63,65,68,69,70,71

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found, in CD4+ and CD8+ cells from patients with Graves disease, hypermethylated CpG sites in genes involved in T cell signalling.36 Other authors have found both hypermethylation30,37 and hypomethylation30,37,38 in genes involved in the immune and inflammatory response in peripheral blood leukocytes from patients with Graves disease

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Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells