PMID: 36703926
If the medication is stopped, appetite can return, and some patients regain a significant amount of weight
When Metformin Remains a First-Line Choice Metformin remains the standard initial medication for type 2 diabetes because it is affordable, well-tolerated, has decades of safety data, and addresses insulin resistancethe root driver of many metabolic disorders
doi: 10.1096/fj.11-201426 159 PiletzJ
Since EDS-related motility issues impact both structure and functioning of the MMC, SIBO for these clients often requires long-term management with prokinetics, dietary strategies, and periods of reducing the bacteria and archaea that may continuously overgrow
Equally useful whenever food intake falls - whether thats dieting, low appetite days or eating plant-based