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329 : 587588 Hanley M, Jackson T

Regulating blood sugar levels to enhance energy and metabolic health

Pediatrics 1969;43:463-5

Specific assays now detect a variety of insulins including human insulin, animal insulin, and insulin analogs (Andersen, Jorgensen, Jensen et al., 2000, Bowsher, Lynch, Brown-Augsburger et al., 1999, Moriyama, Hayashi, Ohyabu et al., 2006, Neal, 2008, Walfish, Feig and Bauman, 1987)

There are multiple effects of these peptides, including lowering blood sugars which was the intended use for diabetes

Specifically, we injected Cre-dependent AAVs encoding either the hM3Dq DREADD (Designer Receptors Exclusively Activated by Designer Drugs) for reversible activation or an AAV encoding taCasp3 for targeted neuron ablation, in Pnoc-Cre transgenic mice