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No impact on the LC-HRMS/MS identification of the analytes was observed, and the methods robustness was demonstrated

In general, these products have short terms effects and most of time nonproductive effects

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Published pre-clinical studies have used FOXO4-DRI to demonstrate that selective elimination of senescent cells in aged mouse models can improve a range of tissue function parameters including fitness, fur density, renal function, and liver function establishing the broader research principle that senescent cell burden contributes meaningfully to ageing tissue dysfunction and that its targeted reduction produces measurable functional benefits in experimental models

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Antioxidant supplementation preserves antioxidant response in physical training and low antioxidant intake