Regulatory Toxicology and Pharmacology, 153 , 105715
However, the AngII/AT 1 receptor system influences multiple functions beyond blood pressure, including body water balance, control of vasopressin and oxytocin release and sexual reproduction and behavior, thus undesirable drug-induced effects are possible
doi: 10.1016/j.xcrm.2021.100238 226 MaestasMMIshahakMAugsornworawatPVeronese-PaniaguaDAMaxwellKGVelazco-CruzLet al
In order to be taken up by the liver it has to be degraded to amino acids. [I also wonder- since glutamate is elevated in metabolic disease, and a residue in the GSH tripeptide, might it be that providing glycine or serine to support synthesis could be preferred over glutathione
It has to tolerate food, interact with the microbiome, maintain a protective barrier, and respond appropriately to pathogens or injury
Injecting peptides into the body can be preferred over oral consumption as it bypasses the chances of it being broken down inside the gut
