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The company believes retatrutide "could become an important option for patients with significant weight loss needs and certain complications, including knee osteoarthritis," Kenneth Custer, president of Lilly Cardiometabolic Health, said in a statement

The most commonly reported sensations relate to the gastrointestinal system , reflecting the drug's mechanism of slowing gastric emptying and affecting gut motility

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K22.4 is dyskinesia of the esophagus, the motility code for achalasia, diffuse spasm, or nutcracker esophagus

If you are considering probiotics alongside existing treatments, discuss this with your GP or specialist to ensure there are no contraindications

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