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Lovelle highlights the guts central role in metabolism, explaining that about 70% of the immune system resides in the gut, and its health directly impacts hormonal balance, inflammation, and systemic wellness. Chronic stress, poor diet, and environmental toxins can disrupt the gut microbiome, leading to increased intestinal permeability and inflammation

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Contraindications include personal or family history of medullary thyroid carcinoma, MEN 2 syndrome, or severe gastroparesis

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