STEP-HFpEF and SUMMIT established meaningful benefit in HFpEF
Common injection sites include the abdomen (avoiding the area immediately around the navel), anterior thigh, or upper arm
Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Ma W, Lee HC, Orlowski RZ, Sarbassov DD, Neelapu SS, McDonnell T, Miranda RN, Wang M, Kantarjian H, Konopleva M, Davis RE, Andreeff M
The study was funded by WW International
If you miss a dose, take it as soon as you remember if its within 4 days of your regular injection day
In September, the FDAs Cardiovascular and Renal Drugs Advisory Committee voted 9-3 in patisirans favor, but on Monday, Alnylam announced that the regulator had issued a Complete Response Letter in response to its supplemental New Drug Application in this indication