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While we await better data and guardrails, there will be more GLP-1 mass improvisation

Suppression of normally occurring reactive astrogliosis worsens neurological outcome and inhibits postlesional plasticity, regeneration and repair, as well as a restoration of the blood-brain barrier, which all determine functional tissue remodelling and post-traumatic rehabilitation

Thus, direct GLP-1R signaling in SPNs might have clinical relevance as it may account for increased heart rate, a common side effect of GLP-1R agonist medications 21

The American Diabetes Association Standards of Medical Care and obesity treatment guidelines recognize these medications as effective options for weight management and glycemic control

This is where you can perhaps save some money, and maybe even a little weight

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