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Studies using in situ hybridization and immunohistochemical analysis to assess the neuroanatomical localization of mGluRs demonstrated the presence of high mGluR1 expression levels in the olfactory bulb, cerebellum, thalamus, and hippocampus regions in the rodents brain [28]

* statistically significant

Overexpression of nuclear receptor subfamily 1, group D member 1 (NR1D1)/Rev-Erba, an orphan nuclear receptor, has been shown to enhance the antimycobacterial properties of macrophages and decrease the survival of M.tb by promoting phagosomelysosome maturation through IL-10 repression in human macrophages[53]

These findings were published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging