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The discussion should include what is known, what is uncertain, what alternatives exist, and when treatment should be stopped

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Exenatide use was associated with a 72% reduction (OR = 0.28, 95% CI: 0.13-0.59, p = 0.0008), and liraglutide with a 71% reduction (OR = 0.29, 95% CI: 0.19-0.46, p = 0.0001)