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[8] [9] Consideraciones temporales clave: Fase de titulacin inicial: Variable segn el producto (2-4 semanas para liraglutida, 4-8 semanas para semaglutida, 5 semanas para dulaglutida a dosis mxima) Evaluacin de respuesta: 3-6 meses para valorar eficacia glucmica y ponderal Tratamiento de mantenimiento: continuacin mientras exista beneficio clnico y buena tolerabilidad Reevaluacin peridica: cada 3-6 meses para monitorizar eficacia y tolerabilidad La decisin de continuar el tratamiento debe basarse en la consecucin de objetivos individualizados de HbA1c, reduccin de peso (si es objetivo), tolerabilidad del medicamento y ausencia de contraindicaciones emergentes, segn las recomendaciones de la ADA

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