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Meaning doses lower than what most researchers use may produce comparable neurogenic signaling without the higher systemic exposure

Claimed PT-141 Peptide Benefits vs

Yang L, Zhu W, Zhang X, Zhou X, Wu W, Shen T

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Ann Intern Med 1995

Weight loss : While not the original purpose of these medications, many patients experience significant and sustained weight lossespecially those on higher-dose versions like Wegovy or Zepbound