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Tracking your medication use and health changes can make a big difference

If you drink, keep within recommended limits, avoid binge drinking and discuss your individual situation with your healthcare team

Unlike other incretin-based drugs such as Eli Lillys ZEPBOUND (tirzepatide), which activates both GLP-1 and GIP receptors, MariTide activates GLP-1 while blocking GIP

Starting from a therapeutic dose of 15 mg weekly, the schedule uses the same four-week intervals between each dose reduction

Wine and spirits contain varying alcohol concentrations and carbohydrate loads

The Phase 2 dose-finding trial (N=338), published in the New England Journal of Medicine in 2023 (DOI: 10.1056/NEJMoa2301972), randomized participants with obesity (BMI 30-50) to retatrutide at doses ranging from 0.5mg to 12mg weekly or placebo over 48 weeks