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Prescribing physicians should monitor their patients renal function carefully

Summary Diabetes doesnt only deplete GSH it impairs enzymes in the glutathione system (like glutathione synthetase, -glutamylcysteine synthetase, glutathione peroxidase)

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Many people tend to have high fatigue levels in the first few weeks of treatment

[1] The Use of Semaglutide in Patients With Renal Failure A Retrospective Cohort Study, Endocrine Practice, October 2024

But as a component of a thoughtfully built longevity and optimization protocol, the evidence supports its use in the right clinical profile