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AOD-9604 is a synthetic 15-amino-acid peptide derived from the C-terminal fragment of human growth hormone (hGH 176-191), modified to enhance its fat-metabolizing properties

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Methylation burden & metabolic dysfunction research: Laboratory applications in cellular methylation stress, SAM-cycle imbalance and NAD+ salvage engineering

It works through a different mechanism (fat oxidation via beta-3 adrenergic receptors, not appetite suppression), and that mechanism produces gradual, subtle changes

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This study was designed to systematically investigate the cartilage-protective effects of AOD9604, both alone and in combination with HA, using a well-established collagenase-induced OA rabbit model