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[30] The conjugation process is illustrated by the metabolism of N -acetyl- p -benzoquinone imine (NAPQI)

Studies using genetic senescent cell clearance confirm that therapeutic benefits result specifically from senescence elimination rather than alternative mechanisms, validating FOXO4-DRI's senolytic activity in the context of chemotoxicity

This means use is limited to in-vitro laboratory testing and experimentation in qualified research institutions

DOI: 10.1016/j.bioactmat.2023.08.008

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