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Early histological studies suggested that microglia are relatively abundant in the hippocampus and may mount particularly rapid and robust proinflammatory responses following peripheral immune challenge (Lawson et al., 1990)

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BPC-157 may influence neurotransmitter systems, including dopamine and serotonin pathways, and may reduce oxidative stress in neural tissue

[82], whereby IVC was combined with gemcitabine only, reported similar positive effects, with 6/9 evaluable patients maintaining or improving their performance status