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Acknowledgments The authors are grateful to Claire Vandervenet and Franoise Darthuy for helpful technical assistance, and to Jean-Pierre Bronowicki and the other investigators of the clinical trial from which the samples have been obtained

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In addition to organ-specific toxicity, AAS use has been associated with neuropsychiatric consequences, including mood instability, aggression, depressive symptoms, and the development of dependence syndromes

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Clinical Evidence and GLP-1 Sourcing Considerations GLP-1 medicationswhether semaglutide, tirzepatide, or emerging compoundshave demonstrated clinical efficacy in randomized trials (STEP trials for semaglutide