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"Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes"

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& Kiledjian, M

In addition, in the HFD/STZ-induced SD rat model, Sirt3 overexpression improves painful diabetes neuropathy by activating FoxO3a/PINK1/Parkin-Mediated mitophagy [170]

To evaluate the effects of compound on GPX4 activity, compound was first pre-incubated with purified GPX4 in the assay buffer [Tris-HCl (100 mM, pH 7.4), EDTA (5 mM), Triton X-100 (0.1% v/v), NADPH (0.2 mM), glutathione (3 mM), and glutathione reductase (1 unit)] for 5 min at 37C