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These results indicate that the increased amount of non-12-OH FXR-antagonistic BAs consequent to the decrease in CYP8B1 expression after T3 treatment potentiates GLP-1 production by deactivating the intestinal FXR, thereby improving glucose homeostasis via the augmentation of insulin secretion

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GLP-1 agonists The most prominent peptide-based fat loss treatments are GLP-1 receptor agonists

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Specifically, tear fluid samples for the GSH assay were diluted fourfold, while undiluted samples were used for the GSS assay to ensure the samples remained within the linear detection range

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