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IGF-1 LR3 Mechanism and Receptor Competition IGF-1 LR3 is a synthetic analog of endogenous IGF-1 with two critical modifications: an arginine substitution at position 3 (the 'R3' designation) and a 13-amino-acid N-terminal extension

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Analytical Observations High purity is confirmed through batch testing using highperformance liquid chromatography (HPLC), while mass spectrometry verifies molecular weight and identity

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Even using the lower rate constants for the chemical reaction in models, DHAR appears to be dispensable (Tuzet et al