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Unfortunately, with the possible exception of LPS and I-FABP, validation of these assays against standard permeability measurements and proper clinical validation studies in large groups of patients are missing and can therefore not be recommended to replace the direct permeability tests described above

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Nat Commun 15: 2835, 2024

Being the largest leveraged buyout in history, EA will likely look for more ways to boost revenue to cover interest payments

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Another study revealed that the oral administration of Polygonum cuspidatum aqueous extract in rats with resected exorbital lacrimal glands restored tear volume and Mucin4 (MUC4) expression by mitigating corneal abnormality and the release of inflammatory cytokines [76]